PRESCRIBING IS HASSLE-FREE, WITH NATIONWIDE
AVAILABILITY THROUGH PHIL AND CAREPOINT PHARMACY

How to Use

Product image of Trudhesa™ Precision Olfactory Delivery (POD®) on black background facing left and tilted down
Words "The upper nasal space where few migraine meds have gone before" on black background
Words "The upper nasal space where few migraine meds have gone before" on black background

Watch this brief video to see how straightforward it is to use TrudhesaTM3,4


Patients should follow complete Instructions for Use, provided with product.

TITLE: Be Direct

VOICEOVER: Ok, are you having a migraine attack? Time to be direct. Let’s go. De-box and determine that everything is in good shape. It looks good to me. Next, you install. Just be careful, it can be a little sharp. Well, R is for ready. You ready the POD by priming it. You press firmly 4 times. This is very important. Looks like it’s ready. Now you engage the POD to the nose, and you press like you’re priming. It’s nice and gentle. Now complete your dose in the other nostril. Last step, T is for toss. Get rid of it, throw it away, you do not need it. You only use it once. That’s it! You have a migraine attack? Be direct. And don’t forget to check out these. Stay tuned for the Important Safety Information. For complete administration information, please see the Instruction for Use sheet that comes in each box of Trudhesa.

Be DIRECT.1


See the step-by-step instructions for use included with every prescription of Trudhesa.

Product image of an open Trudhesa™ Precision Olfactory Delivery (POD®) package showing the POD and vial
Product image of an open Trudhesa™ Precision Olfactory Delivery (POD®) package showing the POD and vial
Words "Determine everything is good to go"

Determine everything is good to go

Words "Install vial and POD together"

Install vial and POD together

Words "Ready POD by priming"

Ready POD by priming

Words "Engage POD to nose"

Engage POD to nose

Words "Complete dosing with 1 spray per nostril"

Complete your dose with 1 spray per nostril

Words "Toss as it can only be used once"

Toss as it can only be used once

How to Prescribe

Blue-tinted image of an actor portrayal of Trudhesa™ patient smiling with short hair,  looking to the left
Blue-tinted image of an actor portrayal of Trudhesa™ patient smiling with short hair,  looking to the left

References: 1. Trudhesa. Prescribing information. Impel NeuroPharma; 2021. 2. Shrewsbury SB, Jeleva M, Satterly KH, Lickliter J, Hoekman J. STOP 101: a phase 1, randomized, open-label, comparative bioavailability study of INP104, dihydroergotamine mesylate (DHE) administered intranasally by a I123 Precision Olfactory Delivery (POD®) Device, in healthy adult subjects. Headache. 2019;59(3):394-409. 3. Shrewsbury SB, Joekman J, Jeleva M. Patient acceptability of a novel upper nasal delivery system for dihydroergotamine mesylate using the Precision Olfactory Delivery (POD®) device – results from the open-label STOP 301 trial. Poster presented at: American Headache Society Virtual Annual Scientific Meeting, June 3-6, 2021. 4. Data on File. Impel NeuroPharma. 2020.